Gas-Phase Separation of Benzocaine Protonation Site Isomers and Phenylalanine Using Travelling-Wave Ion Mobility MS
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چکیده
■ ■ Alternative ion mobility gases may provide a better separation of isomeric/isobaric species IN T RO DU C T IO N As part of the newborn metabolic screening protocol, the early identification of babies at risk of a metabolic disorder allows for the correct medical treatment and management of selected inherited disorders. A particularly effective method for the analysis of certain metabolites from dried blood spots, which may indicate a metabolic disorder, is electrospray ionisation combined with tandem mass spectrometry. A number of inherited diseases result in the disruption of the metabolism and transformation of amino acids.
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تاریخ انتشار 2015